Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep603 | Pituitary and Neuroendocrinology | ECE2020

TGF-β increases caspase 3 activation and migration in bronchial carcinoids

Borges de Souza Patricia , Tagliatti Valentina , Capobianco Simonaco , Rosaria Ambrosio Maria , Chiara Zatelli Maria

Introduction: Typical and atypical bronchial carcinoids (TBC and ABC) are well-differentiated neuroendocrine neoplasms (NEN). First-line treatment is radical removal of the primary tumour; however, management of metastatic BC is still challenging. Bronchial carcinoids (BC) may benefit from treatment with mTOR inhibitors, although response rates are moderate. TBC have shown reduced sensibility to mTOR inhibitors respect to ABC, notwithstanding its less aggressive behaviour. PI3...